Participants must adhere to the code of conduct. We follow the comprehensive code established by ASMS.
Preliminary Schedule: This schedule is subject to change and will be updated as additional details are finalized.
Schedule
Sunday, July 26
8:00am (1h)
Registration Desk opens
9:00am (2:30h)
Tutorial session 1
- Antibodies and transcriptomics, sample prep to acquisition
Caleb Marlin ( The Oklahoma Medical Research Fund)
Thai Palm (Vanderbilt University)
11:30am (2h)
Off-campus independent lunch – midtown Nashville
Registration Desk opens
1:30pm (2:30h)
Tutorial session 2
- Leveraging generative AI for data analysis
Nico Verbeek (Aspect Analytics)
Sadi Quinones-Al-Muhtaseb (University of Florida)
4:00pm (1h)
Registration desk opens + Vendor visit break
5:00pm (1:30h)
Opening address by Prof. Jeffrey Spraggins
Plenary: Prof. Ken Lau (Vanderbilt University)
6:30pm (30m)
Posters setup
Explore Nashville
Monday, July 27
8:00am (30min)
Registration Desks opens
8:30am (2h)
Oral Session 1: Microscopy-Enhanced MSI
Chairs:
- Timothy Trinklein (University of Illinois Urbana-Champaign)
- Kyle Duncan (Vancouver Island University)
8:30am Alyssa Moore, Purdue University: “Understanding Neuronal Excitability using Mass Spectrometry Imaging of SCN2A-deficient Organoids”
8:50am Siva Swapna Kasarla, Johns Hopkins Medicine Baltimore, MD United States: “A novel MALDI-MSI workflow for imaging polar metabolites and its application to organophosphate neurotoxicity studies”
9:10am Tommy Zhang, Purdue University: “Enhancing on-tissue intact proteoform analysis using multi-segmented capillary electrophoresis”
9:30am Fiorella Yantani, Johns Hopkins University: “OPNA Poisoning and treatment to explore the changes in Metabolism and Lipid Regulation in a Humanized Mouse Model”
9:50am Matthew Bonet, The University of Maryland Baltimore: “Exploring the lipid droplet-associated lipid landscape in mouse hippocampus in neurodegenerative disease”
10:10am Waters – Gold Sponsor talk
10:30am (30min)
Coffee Break
11:00am (1h)
Oral Session 2: Advances in Multimodal Imaging Workflows (part 1)
Chairs:
- Martin Dufresne (Vanderbilt University)
- Cay Tressler (The Johns Hopkins University School of Medicine
11:00am Shanika Weerasinghe, Iowa state university: “Mapping Double-Bond Positional Isomers of Phosphatidylcholines in Zebrafish Using OzMALDI Mass Spectrometry Imaging”
11:20am Maddison Hibbard, University of Illinois -Chicago: “iGAMSI: An immunohistochemistry-compatible framework for single-cell spatiallipidomics in intact neural tissues”
11:40am Tae-Hun Hahm, Johns Hopkins: “FluoMALDI Microscopy: A Multimodal Strategy for Spatial Molecular Discovery Integrating Fluorescence Labeling Strategies with MALDI Imaging”
12:00pm (1:30h)
HTX – Sponsored lunch
1:30pm (2h)
Oral Session 2: Advances in Multimodal Imaging Workflows (part 2)
1:30pm Lauren Hill, Medical University of South Carolina: “Multi-Omic MALDI MSI to Evaluate Drug-Induced Metabolic Reprogramming of Peripheral Blood Mononuclear Cells at Single Cell Resolution”
1:50pm Jade Macdonald, Vanderbilt University: “Extracellular Matrix, N-Glycan and Immune Cell Remodeling Define Dysplastic Microenvironments in Early-Onset Colorectal Precancer”
2:10pm Conor Convery, Johns Hopkins : “An Analysis of Standard Matrix Deposition Methodology for Three Negative Ion Mode Matrices”
2:30pm Mithunjha Anandakumar, University of Illinois Urbana Champaign: “Learning When to Stop: Adaptive Temporal Acquisition for FT-ICR Mass Spectrometry Imaging”
2:50pm Erin Seeley, UT MD Anderson Cancer Center: “So Much Data, So Little Tissue: New Strategies for Multi-Omics Data Integration”
3:10pm Timothy Trinklein, University of Illinois Urbana-Champaign: “A whole-brain molecular atlas by integrating accelerated MALDI MSI and in vivo MRI”
3:30pm (15min)
Poster Session Sponsored by SynCell
3:45pm (2:15h)
Poster session
Happy Hour – Beer & wine starting at 4PM
6:00pm (1h)
Vendor Demonstrations
Tuesday, July 28
8:30am (2h)
Oral Session 3: Multimodal Imaging of Complex Microenvironments (part 1)
Chairs:
- Angela Kruse (The Ohio State University)
- Tialfi Bergamin de Castro (University of Maryland Baltimore)
8:30am Angela Kruse, The Ohio State University: “A multimodal spatial atlas of lipid metabolism in the human intestine”
8:50am Tialfi Bergamin de Castro, Univeristy of Maryland Baltimore: “Lung multiomics reveals
dynamic molecular remodeling and immune responses in SARS-CoV-2 infected mouse lungs”
9:10am Lauren Emmerson, Vanderbilt University: “Decoding the Molecular Architecture of S. aureus Osteomyelitis via Multimodal Imaging Mass Spectrometry”
9:30am Kyle Duncan, Vancouver Island University: “Spatially resolved metabolomics of optimal cutting temperature compound (OCT)-embedded tumors”
9:50am Marija Velickovic, Pacific Northwest National Lab: “Metabolome-Informed Proteome Imaging of Complex Heterogeneous Biological Systems”
10:10am Robert Ernst, Department of Microbial Pathogenesis – University of Maryland Baltimore:
“Imaging-Guided Analysis of BECC-Adjuvanted Influenza Microneedle Vaccines and Skin
Phospholipid Remodeling”
10:30am (30min)
Coffee Break
11:00am (1h)
Oral Session 3: Multimodal Imaging of Complex Microenvironments (part 2)
11:00am Kristine Glunde, Johns Hopkins Applied Imaging Mass Spectrometry (AIMS) Core, Radiology Department, Johns Hopkins School of Medicine: “FluoMALDI, RaMALDI, and QMALDI expand MALDI imaging by enabling precise spatial targeting, multimodal integration, and quantitative analysis, providing powerful tools for understanding complex tissue microenvironments”
11:20am Stephanie Cologna, Department of Chemistry, University of Illinois Chicago: “Comprehensive investigation of spatiotemporal lipid alterations in the whole brain of NPC1 mouse models using mass spectrometry imaging”
11:40am Sizun Jiang, Beth Israel Deaconess Medical Center/Harvard Medical School: Fantastic Cells and Where to Find Them
12:00pm (1:30h)
Agilent – Sponsored lunch
1:30pm (1h)
Oral Session 4: Spatial Multi-Omics from Single Tissue Sections
Chairs:
- Erin Seeley (MD Anderson)
- Jade MacDonald (Vanderbilt University)
1:30pm Megan Ward, Vanderbilt University: “Segment-Resolved Lipidomic Exploration of the Human Proximal Tubule using Integrated MALDI IMS and Multiplexed Immunofluorescence”
1:50pm Gargey Yagnik, Ambergen, Inc.: “Multiplexed, Multiomic and Multimodal DESI-immunohistochemical Imaging of Biomarkers Including Drugs in Tissues using Novel Photocleavable Mass-Tag Antibody Probes”
2:10pm Bruker – Gold Sponsor talk
2:30pm Christopher Anderton, Pacific Northwest National Lab: “MOSAICS: An End-to-End Spatial Multiomics Approach for Analyzing a Single Tissue Section”
2:50pm (10min)
Coffee Break
3:00pm (30min)
IMSIS business meeting
Awards
3:30pm (1h)
Closing plenary and State of the Field by Peggi Angel
4:30pm (30min)
Farewells and Unofficial Happy Hour